Polyethylene Glycol (PEG) can stabilize and prolong the therapeutic efficacy of biological drugs. PEG-associated products and drugs including COVID-19 mRNA vaccines, could cause severe allergic reactions called anaphylaxis, which is life threatening. Detection of preexisting and/or induced anti-PEG IgE can identify vulnerable individuals who are hypersensitive to PEG and PEG-contained vaccines and drugs. This detection can improve PEG -related drug safety, which should not be ignored (See more in Literature).
Skin testing, both skin prick testing and intradermal testing, are widely used for screening type I hypersensitivity. However, this kind of testing itself could induce systemic reaction, including anaphylaxis. Recently, the World Allergy Organization Anaphylaxis Committee “advise clinicians to consider obtaining venous access prior to skin testing with PEGs, in patients with a history of possible anaphylaxis to PEG” (Turner, et al. 2021). Thanks to the patented technologies, our products can now be used for blood-based assays of anti-PEG antibodies with unbeatable accuracy, sensitivity and specificity.
PEG specific IgE detection Kit is a first-in-class product.
| Catalog Number | Description/ETA | Size | Shop | |
| LLTPEG-000E | human PEG IgE detection kit, RUO/2-3weeks | Kit | Order |  |
| LLTPEG-000G | human PEG IgG detection kit, RUO/2-3weeks | Kit | Order | |
| LLTPEG-000M | human PEG IgM detection kit, RUO/2-3weeks | Kit | Order | |
| LLTPS-000E | human PEG IgE standard, RUO/in stock | ea | Order |  |
| LLTPS-000G | human PEG IgG standard, RUO/in stock | ea | Order | |
| LLTPS-000M | human PEG IgM standard, RUO/in stock | ea | Order | |
| LLTPS-0003 | human PEG IgM, IgG and IgE combined standard set, RUO/in stock | ea | Order | |
| LLTSN-0000 | human PEG IgE negative serum, RUO/in stock | ea | Order | |
| LLTSP-000E | human PEG IgE positive serum, RUO/in stock | ea | Order | |